Isle of Palms Rentals

Compare 57 vacation rentals.
An error was detected and reported for this component.
USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway

Looking for a peaceful getaway to South Carolina’s sandy beaches? Our Isle of Palms vacation rentals offer tranquility, set apart from the hustle and bustle, but still close enough to enjoy the charm of Charleston. Whether you're looking for family fun or a romantic escape, the Isle of Palms has something for everyone.

Explore Isle of Palms house rentals, villas, condo rentals, and more

housing_type_house.jpg

House rentals

View 22 House rentals
housing_type_villa.jpg

Villas

View 22 Villas
housing_type_condo.jpg

Condo rentals

View 11 Condo rentals

Popular amenities for Isle of Palms vacation rentals

Popular
Dog-friendly Hot tub Internet
128 Grand Pavilion
4 Bedroom | 4 Bath | Sleeps 12

128 Grand Pavilion - Isle of Palms, SC

$595 avg / night
4.57 (54)
Seascape 218
2 Bedroom | 2 Bath | Sleeps 6

Seascape 218 - Isle of Palms, SC

$387 avg / night
4.39 (62)
Lagoon Villa 24
2 Bedroom | 2 Bath | Sleeps 6

Lagoon Villa 24 - Isle of Palms, SC

$213 avg / night
4.04 (49)
Sea Cabin 121-B
1 Bedroom | 1 Bath | Sleeps 4

Sea Cabin 121-B - Isle of Palms, SC

$201 avg / night
4.17 (18)
Sea Cabin 342-C
1 Bedroom | 1 Bath | Sleeps 3

Sea Cabin 342-C - Isle of Palms, SC

$372 avg / night
4.3 (46)

View 52 more homes

Recent Isle of Palms guest reviews

Together with my family of 5 we had an amazing stay in Vacasa during this spring break. The property stood up 100% to the description provided on VRBO. The house was very clean, spacious, with beautiful backyard blooming with pink azaleas bushes, palm trees and oaks. The bed sheets and towels very crisp clean and the kitchen was fully stocked with dishes, amenities and silverware. The pool water was very clean and on a cooler side but, considering I do cold plunging regularly, it was perfect. Kids didn’t mind it at all and jumped right into it. The house is located literally 3 min walk to the beach which is more private since all the small hotels are further south and the beach was not crowded at all. A lot of parking space for our SUV in front of the house. Friendly neighbors and amazing location of the house on the Isle of Palms. There was a bike store and great cafe (Cafe Paname) about 8 min walk from the house so we rented bikes for $25 per person for the 24 period and biked the entire island and grabbed fresh crossings and delicious coffee at the cafe next doors. Overall, we rate the stay, location, house 10/10 and recommend it deeply. Thank you Vacasa for fantastic time!
Dawid B. | Apr 2025
We were on the Isle of Palms for a wedding. This was a great place for our family to stay. The beach is beautiful. It was not crowded. The condo had a nice outdoor space. Would definitely go back there to stay. Highly recommend.
Vicki A. | Apr 2025
We loved how close to the beach the property was and the overall house. Great location.
Brayden W. | Apr 2025
Isle of Palms vacation rental FAQ

Yes, 25 of our Isle of Palms homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 105 of our Isle of Palms vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Isle of Palms vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find the check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Isle of Palms team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No problem, plans can change. For more information, please read our cancellation policy. If you have a Vacasa reservation for Isle of Palms, log in to Trip Manager to explore the options available for your specific trip.

Book confidently. Stay comfortably.

Vacasa Guest Value Prop icon: 24-7
24/7 guest service
Vacasa Guest Value Prop Icon check-in
Seamless check-in
Vacasa Guest Value Prop Icons cleaning
Professional cleaning

Explore Isle of Palms, SC

Nestled on a beautiful barrier island, Isle of Palms is just 18 miles from Charleston and about 130 miles from Columbia. This idyllic location is perfect for beachgoers and nature lovers alike. The island's long stretches of beach are home to sea turtles, and if you’re lucky, you might witness local professionals helping these tiny creatures make their way to the ocean.

Things to do in Isle of Palms, SC

From beach fun to exploring nearby islands, there's no shortage of activities to enjoy during your stay.

Where is Isle of Palms, SC?

Located just off the coast of South Carolina, Isle of Palms is a barrier island near Charleston. It offers easy access to both the serene beauty of the ocean and the vibrant culture of Charleston, making it an ideal spot for vacationers looking to experience the best of both worlds.

Book an Isle of Palms vacation rental

Whether you're visiting for the beaches, the history, or just to unwind, our Isle of Palms vacation rentals provide the perfect retreat. With a range of homes featuring ocean views, spacious patios, and family-friendly amenities, you're sure to find a spot that fits your getaway vision. Browse our collection of Isle of Palms vacation homes and get ready for a relaxing escape on South Carolina’s coast.